Cancer-miRNA Regulatory Network

Compendium of miRNA Target Genes

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MPM Mesothelioma Gordon Cluster Number 7 (59 genes) This page contains all miRNA mediated regulation and functional enrichment for MPM Mesothelioma Gordon cluster number 7. Information about mesothelioma can be found on Wikipedia, and further information about the "MPM Mesothelioma Gordon" dataset can be found in Gordon et al., 2005. Inferred miRNA Mediated Regulation Weeder-miRvestigator PITA TargetScan zzz999 hsa-mir-526b zzz999 Gene Ontology Enrichment GO ID GO Term Annotated Genes in Cluster GO:0001816 cytokine production 8 GO:0001817 regulation of cytokine production 7 GO:0001818 negative regulation of cytokine production 6 GO:0002376 immune system process 28 GO:0006952 defense response 30 GO:0006955 immune response 26 GO:0007165 signal transduction 29 GO:0007166 cell surface receptor linked signaling pathway 21 GO:0009057 macromolecule catabolic process 11 GO:0009607 response to biotic stimulus 17 GO:0009615 response to virus 16 GO:0019060 intracellular transport of viral proteins in host cell 2 GO:0019221 cytokine-mediated signaling pathway 20 GO:0019941 modification-dependent protein catabolic process 8 GO:0030163 protein catabolic process 8 GO:0030581 symbiont intracellular protein transport in host 2 GO:0032020 ISG15-protein conjugation 3 GO:0032479 regulation of type I interferon production 6 GO:0032480 negative regulation of type I interferon production 6 GO:0032606 type I interferon production 7 GO:0043632 modification-dependent macromolecule catabolic process 8 GO:0044257 cellular protein catabolic process 8 GO:0044265 cellular macromolecule catabolic process 11 GO:0044419 interspecies interaction between organisms 10 GO:0046719 regulation of viral protein levels in host cell 2 GO:0050896 response to stimulus 40 GO:0051603 proteolysis involved in cellular protein catabolic process 8 GO:0051704 multi-organism process 21 GO:0051707 response to other organism 16 GO:0051708 intracellular protein transport in other organism involved in symbiotic interaction 2 GO:0060333 interferon-gamma-mediated signaling pathway 6 GO:0060337 type I interferon-mediated signaling pathway 20 Overlap Between miRNA Target Genes and Enriched Gene Ontology Annotations miRNA Method GO ID GO Term Overlap GO Annotated Genes Cluster Size miRNA Targets Genes P-Value hsa-mir-526b PITA GO:0001816 cytokine production 0 8 59 3 0.3594082 hsa-mir-526b PITA GO:0001817 regulation of cytokine production 0 7 59 3 0.3201883 hsa-mir-526b PITA GO:0001818 negative regulation of cytokine production 0 6 59 3 0.2793996 hsa-mir-526b PITA GO:0002376 immune system process 0 28 59 3 0.8617306 hsa-mir-526b PITA GO:0006952 defense response 0 30 59 3 0.8876004 hsa-mir-526b PITA GO:0006955 immune response 0 26 59 3 0.8321696 hsa-mir-526b PITA GO:0007165 signal transduction 3 29 59 3 0.0 hsa-mir-526b PITA GO:0007166 cell surface receptor linked signaling pathway 0 21 59 3 0.7405026 hsa-mir-526b PITA GO:0009057 macromolecule catabolic process 1 11 59 3 0.0862838 hsa-mir-526b PITA GO:0009607 response to biotic stimulus 0 17 59 3 0.646867 hsa-mir-526b PITA GO:0009615 response to virus 0 16 59 3 0.620382 hsa-mir-526b PITA GO:0019060 intracellular transport of viral proteins in host cell 0 2 59 3 0.09994155 hsa-mir-526b PITA GO:0019221 cytokine-mediated signaling pathway 0 20 59 3 0.7188778 hsa-mir-526b PITA GO:0019941 modification-dependent protein catabolic process 1 8 59 3 0.0456489 hsa-mir-526b PITA GO:0030163 protein catabolic process 1 8 59 3 0.0456489 hsa-mir-526b PITA GO:0030581 symbiont intracellular protein transport in host 0 2 59 3 0.09994155 hsa-mir-526b PITA GO:0032020 ISG15-protein conjugation 0 3 59 3 0.1473131 hsa-mir-526b PITA GO:0032479 regulation of type I interferon production 0 6 59 3 0.2793996 hsa-mir-526b PITA GO:0032480 negative regulation of type I interferon production 0 6 59 3 0.2793996 hsa-mir-526b PITA GO:0032606 type I interferon production 0 7 59 3 0.3201883 hsa-mir-526b PITA GO:0043632 modification-dependent macromolecule catabolic process 1 8 59 3 0.0456489 hsa-mir-526b PITA GO:0044257 cellular protein catabolic process 1 8 59 3 0.0456489 hsa-mir-526b PITA GO:0044265 cellular macromolecule catabolic process 1 11 59 3 0.0862838 hsa-mir-526b PITA GO:0044419 interspecies interaction between organisms 0 10 59 3 0.4332646 hsa-mir-526b PITA GO:0046719 regulation of viral protein levels in host cell 0 2 59 3 0.09994155 hsa-mir-526b PITA GO:0050896 response to stimulus 3 40 59 3 0.0 hsa-mir-526b PITA GO:0051603 proteolysis involved in cellular protein catabolic process 1 8 59 3 0.0456489 hsa-mir-526b PITA GO:0051704 multi-organism process 0 21 59 3 0.7405026 hsa-mir-526b PITA GO:0051707 response to other organism 0 16 59 3 0.620382 hsa-mir-526b PITA GO:0051708 intracellular protein transport in other organism involved in symbiotic interaction 0 2 59 3 0.09994155 hsa-mir-526b PITA GO:0060333 interferon-gamma-mediated signaling pathway 0 6 59 3 0.2793996 hsa-mir-526b PITA GO:0060337 type I interferon-mediated signaling pathway 0 20 59 3 0.7188778

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